LP23
Product Specifications
Target
PD-1/PD-L1
Related Pathways
Apoptosis|||Cell Cycle/Checkpoint|||Immunology/Inflammation
Bioactivity
LP23, a non-arylmethylamine PD-1/PD-L1 inhibitor (IC 50: 16.7 nM), exhibits anti-tumor activity through the restoration of immune cell function in HepG2/Jurkat T cells and induction of HepG2 cell death. Additionally, LP23 demonstrates in vivo efficacy in the B16-F10 tumor model (TGI=88.6% at 30 mg/kg) [1].
Molecular Formula
C27H27N3O5S
Molecular Weight
505.59
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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