PI3K-IN-48
Product Specifications
Target
PI3K, Akt
Related Pathways
Cytoskeletal Signaling, PI3K/Akt/mTOR signaling
Bioactivity
PI3K-IN-48, a PI3K inhibitor, exhibits an IC50 of 1.55 ± 0.18 μM in A549 cells, demonstrating its potency in this context. It induces G0/G1 phase arrest and cell apoptosis, while also down-regulating the expression of p-PI3K and p-Akt. This compound is relevant for research into the treatment of human lung cancers [1].
Molecular Formula
C25H21FN2O4
Molecular Weight
432.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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