NLRP3-IN-19
Product Specifications
CAS Number
2238819-65-1
Target
NOD-like Receptor (NLR)
Related Pathways
Immunology/Inflammation
Bioactivity
JT001 (NLRP3-IN-19) is a potent, specific, and orally active NLRP3 inhibitor that impedes the assembly of the NLRP3 inflammasome, suppressing cytokine release and preventing pyroptosis. JT001 is utilized in research on nonalcoholic steatohepatitis and liver fibrosis [1].
Smiles
N(C(NS(=O)(=O)C1=C2N(N=C1)CCCO2)=O)C3=C4C(=CC5=C3CCC5)CCC4
Molecular Formula
C19H22N4O4S
Molecular Weight
402.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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