EGFR-IN-88
Product Specifications
CAS Number
2944452-34-8
Target
Apoptosis, EGFR
Related Pathways
Apoptosis, Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling
Bioactivity
EGFR-IN-88 (Compound 4i), an EGFR inhibitor with an IC50 of 87 nM, exhibits cytotoxic effects on A549 cells at an IC50 of 3.902 μM and can induce cell apoptosis [1].
Smiles
C(C)C1=NC2=C(N=C1CC)C=CC(=C2)C=3OC(SCC(=O)C4=C(Cl)C=C(Cl)C=C4)=NN3
Molecular Formula
C22H18Cl2N4O2S
Molecular Weight
473.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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