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PSEN1-IN-1

Product Specifications

Target

Gamma-secretase, Others

Related Pathways

Proteases/Proteasome, Neuroscience, Others, Stem Cells

Bioactivity

PSEN1-IN-1 (Compound (+) -13b) is an inhibitor of PSEN1, exhibiting strong inhibition of the PSEN1-APH1A and PSEN1-APH1B complexes with IC50 values of 19 nM and 5.5 nM, respectively. It is employed in Alzheimer's disease research [1].

Molecular Formula

C20H19ClF3NO3S

Molecular Weight

445.88

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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