Anti-inflammatory agent 56
Product Specifications
CAS Number
2413127-32-7
Target
COX
Related Pathways
Immunology/Inflammation|||Neuroscience
Bioactivity
Anti-inflammatory agent 56 (Compound 9), a selective COX-2 inhibitor with an IC50 of 0.54 ?M, exhibits antioxidant and anti-inflammatory properties by inhibiting oxidative stress-induced cell death and neuroinflammation through the suppression of Keap1, COX-2, and iNOS. It demonstrates low acute toxicity in mice with an LD50 of 1000 mg/kg [1].
Smiles
OC1=C(C=2N(N=C(N2)C3=C(O)C=C(C(F)(F)F)C=C3)C4=CC=C(S(N)(=O)=O)C=C4)C=CC=C1
Molecular Formula
C21H15F3N4O4S
Molecular Weight
476.43
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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