What is the catalog number for STAT3-IN-20?

The catalog number for STAT3-IN-20 is T79662.

What sizes are available for STAT3-IN-20?

STAT3-IN-20 is available in the following size(s): 25 mg, 50 mg, 100 mg.

How many pack sizes does STAT3-IN-20 come in?

STAT3-IN-20 is available in 3 different pack sizes.

Is STAT3-IN-20 in stock?

STAT3-IN-20 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures STAT3-IN-20?

STAT3-IN-20 is manufactured by Molfinity.

What is the estimated delivery time for STAT3-IN-20?

Estimated delivery time for STAT3-IN-20 is approximately 10 business day(s), depending on your location.

STAT3-IN-20

Product Specifications

CAS Number

2768427-54-7

Target

STAT

Related Pathways

JAK/STAT signaling, Stem Cells

Bioactivity

STAT3-IN-20 (Compound 40), with an IC50 of 0.65 μM, is a selective inhibitor targeting the SH2 domain of STAT3, thereby impeding its phosphorylation, nuclear translocation, and subsequent gene transcription. The compound demonstrates antiproliferative effects on DU145 and MDA-MB-231 cancer cell lines, which have overactivated STAT3, with IC50 values of 2.97 μM and 3.26 μM, respectively. Moreover, STAT3-IN-20 induces cell cycle arrest and apoptosis [1].