MeOIstPyrd
Product Specifications
CAS Number
2308548-54-9
Target
Others|||MDM-2/p53
Related Pathways
Others|||Apoptosis
Bioactivity
MeOIstPyrd is an anti-skin cancer agent that inhibits cell proliferation, migration, and spheroid formation by activating the mitochondrial intrinsic apoptotic pathway. It induces DNA damage, activates p53, increases its half-life, and stabilizes p53 via ser15 phosphorylation. Additionally, MeOIstPyrd interfaces with MDM2 within the p53 sub-pocket, preventing the p53-MDM2 interaction [1].
Smiles
N(\NC(=S)N1CCCC1)=C\2/C=3C(NC2=O)=CC=C(OC)C3
Molecular Formula
C14H16N4O2S
Molecular Weight
304.37
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
