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MeOIstPyrd

Product Specifications

CAS Number

2308548-54-9

Target

Others|||MDM-2/p53

Related Pathways

Others|||Apoptosis

Bioactivity

MeOIstPyrd is an anti-skin cancer agent that inhibits cell proliferation, migration, and spheroid formation by activating the mitochondrial intrinsic apoptotic pathway. It induces DNA damage, activates p53, increases its half-life, and stabilizes p53 via ser15 phosphorylation. Additionally, MeOIstPyrd interfaces with MDM2 within the p53 sub-pocket, preventing the p53-MDM2 interaction [1].

Smiles

N(\NC(=S)N1CCCC1)=C\2/C=3C(NC2=O)=CC=C(OC)C3

Molecular Formula

C14H16N4O2S

Molecular Weight

304.37

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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