Tubulin polymerization-IN-48

Tubulin polymerization-IN-48 (Compound 4k) is a tubulin polymerization inhibitor that moderately disrupts the microtubule network and impedes the proliferation of neuroblastoma cancer cells, with IC50 values of 79 nM and 165 nM for the Chp-134 and Kelly cell lines, respectively [1].