PD-1/PD-L1-IN-33
Product Specifications
CAS Number
2975602-78-7
Target
PD-1/PD-L1
Related Pathways
Immunology/Inflammation, Cell Cycle/Checkpoint, Apoptosis
Bioactivity
PD-1/PD-L1-IN-33 (Compound N11), a PD-1/PD-L1 inhibitor with an IC50 of 6.3 nM, effectively impedes the interaction between PD-1 and PD-L1. It enhances T-cell proliferation, activation, and infiltration within tumor environments, thereby exhibiting immunomodulatory and anticancer properties [1].
Smiles
C(NC(CO)(C)C)C1=CC2=C(C(N3C=4C(CC3)=C(C=CC4)C5=CC=CC=C5)=NC=N2)N=C1
Molecular Formula
C26H27N5O
Molecular Weight
425.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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