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MS9715

Product Specifications

Target

PROTACs|||Histone Methyltransferase

Related Pathways

Chromatin/Epigenetic|||PROTAC

Bioactivity

MS9715 is a potent and selective NSD3-targeting PROTAC, designed by leveraging BI-9321, which targets the PWWP1 domain of NSD3, in conjunction with an E3 ligase VHL ligand. This compound holds potential for research in NSD3-dependent cancer treatments [1].

Smiles

CC1=CC(CNCCCC(NCCCCCCCCC(N[C@@H](C(C)(C)C)C(N2[C@H](C(N[C@@H](C)C3=CC=C(C4=C(C)N=CS4)C=C3)=O)C[C@@H](O)C2)=O)=O)=O)=CC(C)=C1C5=C(C6=CC=NC7=C6C=CC(F)=C7)N(C)C=N5

Molecular Formula

C58H74FN9O5S

Molecular Weight

1028.33

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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