CAF-382
Product Specifications
Target
CDK
Related Pathways
Cell Cycle/Checkpoint
Bioactivity
CAF-382 (compound B1), an analog of SNS-032, functions as a CDKL5 and pan-CDK inhibitor, exhibiting modest inhibitory activity against GSK3α/β with an affinity greater than 1.8 μM. It effectively inhibits CDKL5 and impedes the phosphorylation of the CDKL5 E2 domain [1].
Molecular Formula
C16H22N4O2S2
Molecular Weight
366.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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