PARP1-IN-14
Product Specifications
CAS Number
2098639-70-2
Target
PARP|||Apoptosis
Related Pathways
Chromatin/Epigenetic|||DNA Damage/DNA Repair|||Apoptosis
Bioactivity
PARP1-IN-14 (compound 19k) is a potent PARP1 inhibitor with an IC50 of 0.6 ± 0.1 nM, displaying antiproliferative effects on MDA-MB-436 (BRCA1 ?/?) and Capan-1 (BRCA2 ?/?) cells, with IC50 values below 0.3 nM [1].
Smiles
CC1N2C(=NN=C2CN(C(=O)C3=CC(CC=4C=5C(C(=O)NN4)=CC=CC5)=CC=C3F)C1)C=6N=C(OC)C=CC6
Molecular Formula
C28H24FN7O3
Molecular Weight
525.53
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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