COX-1/2-IN-4

COX-1/2-IN-4 (compound 2b) is a dual COX-1 and COX-2 inhibitor with IC50 values of 0.239 ?M for COX-1 and 0.191 ?M for COX-2, and demonstrates moderate anticancer activity with IC50 values of 30.79 ?M against COLO205 cancer cell lines and 74.15 ?M against B16F1 cancer cell lines [1].