DdUTP
Product Specifications
CAS Number
84445-38-5
Target
Reverse Transcriptase
Related Pathways
Microbiology/Virology
Bioactivity
DdUTP (2′,3′-Dideoxyuridine-5′-triphosphate) is a selective inhibitor of HIV and AMV reverse transcriptases, with Ki values of 0.05 μM for HIV and 1 μM for AMV. It is preferentially incorporated at dTTP sites within the DNA strand, thereby preventing further chain elongation [1].
Smiles
[O-]P([O-])(=O)OP([O-])(=O)OP([O-])(=O)OC[C@@H]1CC[C@@H](O1)n1ccc(=O)[nH]c1=O
Molecular Formula
C9H15N2O13P3
Molecular Weight
448.111
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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