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DdUTP

Product Specifications

CAS Number

84445-38-5

Target

Reverse Transcriptase

Related Pathways

Microbiology/Virology

Bioactivity

DdUTP (2?,3?-Dideoxyuridine-5?-triphosphate) is a selective inhibitor of HIV and AMV reverse transcriptases, with Ki values of 0.05 µM for HIV and 1 µM for AMV. It is preferentially incorporated at dTTP sites within the DNA strand, thereby preventing further chain elongation [1].

Smiles

[O-]P([O-])(=O)OP([O-])(=O)OP([O-])(=O)OC[C@@H]1CC[C@@H](O1)n1ccc(=O)[nH]c1=O

Molecular Formula

C9H15N2O13P3

Molecular Weight

448.111

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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