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AChE/Aβ-IN-2

Product Specifications

Target

Others, Cholinesterase (ChE), Beta Amyloid, iGluR

Related Pathways

Neuroscience, Others, Membrane transporter/Ion channel

Bioactivity

AChE/Aβ-IN-2 (compound 33) is a potent, orally active acetylcholinesterase (AChE) inhibitor (IC50: 135 nM), an NMDA receptor antagonist (GluN1-1b/GluN2B subunit combination, IC50: 5.054 μM), inhibits Aβ aggregation, demonstrates favorable blood-brain barrier permeability, and enhances cognitive and spatial memory in a rat model [1].

Molecular Formula

C20H25ClN4

Molecular Weight

356.89

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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