AChE/Aβ-IN-2
Product Specifications
Target
Others, Cholinesterase (ChE), Beta Amyloid, iGluR
Related Pathways
Neuroscience, Others, Membrane transporter/Ion channel
Bioactivity
AChE/Aβ-IN-2 (compound 33) is a potent, orally active acetylcholinesterase (AChE) inhibitor (IC50: 135 nM), an NMDA receptor antagonist (GluN1-1b/GluN2B subunit combination, IC50: 5.054 μM), inhibits Aβ aggregation, demonstrates favorable blood-brain barrier permeability, and enhances cognitive and spatial memory in a rat model [1].
Molecular Formula
C20H25ClN4
Molecular Weight
356.89
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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