AChE/Aβ-IN-1
Product Specifications
Target
Others, Cholinesterase (ChE), Beta Amyloid, iGluR
Related Pathways
Neuroscience, Others, Membrane transporter/Ion channel
Bioactivity
AChE/Aβ-IN-1 (compound 32) is a potent, orally active acetylcholinesterase (AChE) inhibitor with an IC50 of 86 nM and an NMDA receptor antagonist targeting the GluN1-1b/GluN2B subunit combination with an IC50 of 3.876 μM. It also impedes Aβ aggregation, exhibits favorable blood-brain barrier permeability, offers neuroprotection, and enhances cognitive and spatial memory in rat models [1].
Molecular Formula
C20H25BrN4
Molecular Weight
401.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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