Sirt1/2-IN-4
Product Specifications
Target
Sirtuin
Related Pathways
Chromatin/Epigenetic, DNA Damage/DNA Repair
Bioactivity
Sirt1/2-IN-4 (compound PS3) is a potent triple inhibitor of SIRT1, SIRT2, and SIRT3, exhibiting IC50 values of 1.2 μM (SIRT1), 1.9 μM (SIRT2), and 18.6 μM (SIRT3), respectively. It effectively inhibits p53 deacetylation, indicating potential anticancer properties [1].
Molecular Formula
C21H20N4O3S2
Molecular Weight
440.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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