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Sirt1/2-IN-4

Product Specifications

Target

Sirtuin

Related Pathways

Chromatin/Epigenetic, DNA Damage/DNA Repair

Bioactivity

Sirt1/2-IN-4 (compound PS3) is a potent triple inhibitor of SIRT1, SIRT2, and SIRT3, exhibiting IC50 values of 1.2 μM (SIRT1), 1.9 μM (SIRT2), and 18.6 μM (SIRT3), respectively. It effectively inhibits p53 deacetylation, indicating potential anticancer properties [1].

Molecular Formula

C21H20N4O3S2

Molecular Weight

440.54

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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