What is the catalog number for Sirt1/2-IN-2?

The catalog number for Sirt1/2-IN-2 is T79563.

What sizes are available for Sirt1/2-IN-2?

Sirt1/2-IN-2 is available in the following size(s): 5 mg, 50 mg.

How many pack sizes does Sirt1/2-IN-2 come in?

Sirt1/2-IN-2 is available in 2 different pack sizes.

Is Sirt1/2-IN-2 in stock?

Sirt1/2-IN-2 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Sirt1/2-IN-2?

Sirt1/2-IN-2 is manufactured by Molfinity.

What is the estimated delivery time for Sirt1/2-IN-2?

Estimated delivery time for Sirt1/2-IN-2 is approximately 10 business day(s), depending on your location.

Sirt1/2-IN-2

Product Specifications

CAS Number

670267-73-9

Target

Apoptosis, Sirtuin

Related Pathways

Apoptosis, Chromatin/Epigenetic, DNA Damage/DNA Repair

Bioactivity

Sirt1/2-IN-2 (compound hsa55) is a dual inhibitor, targeting SIRT1 with an IC50 of 1.8 μM and SIRT2 with an IC50 of 2.4 μM. It effectively inhibits p53 deacetylation while enhancing the acetylation of p53 and α-tubulin, promoting apoptosis and exhibiting anti-proliferative effects on human leukemia cell lines [1].