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Leucettinib-92

Product Specifications

CAS Number

2732859-57-1

Target

CDK, DYRK

Related Pathways

Tyrosine Kinase/Adaptors, Cell Cycle/Checkpoint

Bioactivity

Leucettinib-92 (compound 92) is a kinase inhibitor selective for the DYRK/CLK families, with IC50 values of 147 nM for CLK1, 39 nM for CLK2, 5.2 nM for CLK4, 0.8 μM for CLK3, 124 nM for DYRK1A, 204 nM for DYRK1B, 0.16 μM for DYRK2, 1.0 μM for DYRK3, 0.52 μM for DYRK4, and 2.78 μM for GSK3 [1].

Smiles

N(C12CC3CC(C1)CC(C2)C3)C=4N/C(=C\C=5C=C6C(=CC5)N=CS6)/C(=O)N4

Molecular Formula

C21H22N4OS

Molecular Weight

378.49

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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