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Mtb-IN-4

Product Specifications

CAS Number

2306039-13-2

Target

Others, Antibacterial

Related Pathways

Others, Microbiology/Virology

Bioactivity

Mtb-IN-4 (compound 17h) is a non-toxic isoxazole that exhibits anti-Mycobacterium tuberculosis (Mtb) activity with an IC50 value of 0.70 μM. It impedes Mtb respiration and biofilm formation within macrophages and augments the efficacy of the antibiotic isoniazid (INH) against INH-resistant Mtb mutants [1].

Smiles

C(O)(=O)C1N2C(=C(C(=CC2=O)C3=CC(=NO3)C4=CC5=C(C=C4)C=CC=C5)C6CC6)SC1

Molecular Formula

C24H18N2O4S

Molecular Weight

430.48

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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