Fac-[Re (CO) 3 (L3) (H2O) ][NO3]
Product Specifications
Target
Apoptosis, Others
Related Pathways
Apoptosis, Others
Bioactivity
Fac-[Re (CO) 3 (L3) (H2O) ][NO3] (Compound 3), a rhenium (I) tricarbonyl aqua complex, acts as an anticancer agent through the induction of mitochondrial dysfunction. It exhibits cytotoxicity against prostate cancer cells, demonstrating an IC50 value of 0.32 μM in PC-3 cells. This compound predominantly localizes to the mitochondria, reducing ATP production and triggering paraptosis in PC3 cells, while not initiating necrosis, apoptosis, or autophagy [1].
Molecular Formula
C25H17N6O8Re
Molecular Weight
715.64
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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