Fac-[Re (CO) 3 (L6) (H2O) ][NO3]

Compound 6, fac-[Re (CO) 3 (L6) (H2O) ][NO3], a rhenium (I) tricarbonyl aqua complex, serves as an anticancer agent by disrupting mitochondrial function. It exhibits cytotoxicity against prostate cancer cells with an IC50 of 50 nM in PC-3 cells. This compound predominantly localizes in the nucleus, impairs ATP production, and induces apoptosis in PC3 cells without causing necrosis, pyroptosis, or autophagy [1].