AChE-IN-34

AChE-IN-34 (compound 5l) is a potent and selective AChE inhibitor with an IC50 of 3.98 μM, exhibiting negligible BChE inhibition. It demonstrates mixed-mode inhibition of AChE with a Ki of 0.044 μM using acetylthiocholine substrate concentrations ranging from 0.1-1 mM [1].