HCA/VEGFR-2-IN-1
Product Specifications
Target
Carbonic Anhydrase, VEGFR
Related Pathways
Metabolism, Angiogenesis, Tyrosine Kinase/Adaptors
Bioactivity
HCA/VEGFR-2-IN-1 (compound 13a) is a potent dual inhibitor targeting both Carbonic Anhydrase (CA) IX/XII and Vascular Endothelial Growth Factor Receptor 2 (VEGFR-2), exhibiting Ki values of 4.7 nM for hCA XII and 8.3 nM for hCA IX, alongside an IC50 of 26.3 nM for VEGFR-2, and demonstrating anticancer activity [1].
Molecular Formula
C21H17FN6O3S
Molecular Weight
452.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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