SWS1
Product Specifications
CAS Number
2922115-32-8
Target
PD-1/PD-L1, Monoamine Oxidase
Related Pathways
Apoptosis, Neuroscience, Immunology/Inflammation, Cell Cycle/Checkpoint
Bioactivity
SWS1, a d- (+) -biotin-conjugated PD-L1 inhibitor (IC50: 1.8 nM), displays anticancer activity by augmenting tumor-infiltrating lymphocytes and demonstrating anti-tumor efficacy, as evidenced by a 66.1% tumor growth inhibition (TGI=66.1%) in the B16-F10 mouse model [1].
Smiles
C(CCCC(NCCNC(=O)C1N(CC2=C(OCC3=CC(C#N)=CC=C3)C=C(OCC4=C(C)C(=CC=C4)C5=CC=CC=C5)C(Cl)=C2)CCCC1)=O)[C@H]6[C@@]7([C@](CS6)(NC(=O)N7)[H])[H]
Molecular Formula
C47H53ClN6O5S
Molecular Weight
849.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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