ABCG2-IN-1
Product Specifications
CAS Number
2559759-40-7
Target
BCRP
Related Pathways
Membrane transporter/Ion channel
Bioactivity
ABCG2-IN-1 (compound K2), an analog of Ko143, is an orally active inhibitor of ABCG2 with an IC50 of 0.13 ?M, demonstrating favorable oral pharmacokinetics in mice and showing promise for further research [1].
Smiles
C(C(C)C)[C@H]1C2=C(C=3C(N2)=CC(OC)=CC3)C[C@@]4(N1C(=O)[C@H](CCC(NC(C)(C)C)=O)NC4=O)[H]
Molecular Formula
C26H36N4O4
Molecular Weight
468.59
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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