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PROTAC TG2 degrader-1

Product Specifications

Target

PROTACs|||Glutaminase

Related Pathways

Proteases/Proteasome|||PROTAC

Bioactivity

PROTAC TG2 Degrader-1 (Compound 11) is a VHL-based PROTAC that targets tissue transglutaminase (TG2) and exhibits a binding affinity with a K D of 68.9 ?M. This compound effectively decreases TG2 levels in ovarian cancer cells through a proteasome-dependent pathway [1].

Molecular Formula

C55H73N9O10S

Molecular Weight

1052.29

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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