PROTAC TG2 degrader-1
Product Specifications
Target
PROTACs|||Glutaminase
Related Pathways
Proteases/Proteasome|||PROTAC
Bioactivity
PROTAC TG2 Degrader-1 (Compound 11) is a VHL-based PROTAC that targets tissue transglutaminase (TG2) and exhibits a binding affinity with a K D of 68.9 ?M. This compound effectively decreases TG2 levels in ovarian cancer cells through a proteasome-dependent pathway [1].
Molecular Formula
C55H73N9O10S
Molecular Weight
1052.29
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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