SCAL-255
Product Specifications
CAS Number
2798953-61-2
Target
OXPHOS, Mitochondrial Metabolism
Related Pathways
Apoptosis, Metabolism
Bioactivity
SCAL-255 is a mitochondrial complex I (CI) inhibitor, exhibiting potent inhibition with an IC50 of 1.14 μM. It impedes mitochondrial function by blocking oxygen consumption rate (OCR), inducing reactive oxygen species (ROS) production, and diminishing mitochondrial membrane potential (MMP) . Furthermore, SCAL-255 significantly hampers the proliferation of cancer cells reliant on oxidative phosphorylation (OXPHOS) [1].
Smiles
C(C=1C=C(N2CCN(C(=O)C3CC3)CC2)C=CC1)N4N=C(C(NC5=CC=C(OC(F)(F)F)C=C5)=O)C=C4C
Molecular Formula
C27H28F3N5O3
Molecular Weight
527.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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