ROR? antagonist 1
Product Specifications
Target
ROR
Related Pathways
Metabolism
Bioactivity
ROR? antagonist 1 (compound 22), a potent derivative of betulinic acid, acts as an antagonist to ROR? with a dissociation constant (K D) of 0.18 ?M. It demonstrates anti-proliferative effects in the HPAF-II pancreatic cancer xenograft model, inhibits the RAS/MAPK and AKT/mTORC1 signaling pathways, and triggers caspase-dependent apoptosis in pancreatic cancer cells [1].
Molecular Formula
C35H60N2O2
Molecular Weight
540.86
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/123792164189634785/T79464
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
