YF704

Product Specifications

Target

Phosphatase|||Others

Related Pathways

Others|||Metabolism

Bioactivity

YF704 (compound 4w), a selective allosteric inhibitor of SHP2, exhibits antiproliferative effects and induces apoptosis in cancer cells with an IC50 of 0.25 ?M. Furthermore, it downregulates Erk1/2 and Akt phosphorylation levels in cancer cells [1].

Molecular Formula

C17H20Cl2N4OS2

Molecular Weight

431.4

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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