PEX5-PEX14 PPI-IN-1
Product Specifications
Target
Others, Antibacterial
Related Pathways
Others, Microbiology/Virology
Bioactivity
PEX5-PEX14 PPI-IN-1 (Compound 8) is a PEX14-PEX5 protein-protein interaction (PPI) inhibitor with an inhibitory constant (Ki) of 53 μM that disrupts the interaction between PEX5 and TbPEX14. It effectively inhibits the bloodstream form of Trypanosoma brucei brucei with a half-maximal effective concentration (EC50) of 5 μM [1].
Smiles
O=C1[C@H](CC2=CNC3=C2C=CC=C3)NCCCN1[C@@H](CC4=CNC5=C4C=CC=C5)C(OC)=O
Molecular Formula
C26H28N4O3
Molecular Weight
444.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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