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BuChE-IN-9

Product Specifications

Target

Others, GABA Receptor, Beta-Secretase, Cholinesterase (ChE)

Related Pathways

Neuroscience, Membrane transporter/Ion channel, Others

Bioactivity

BuChE-IN-9 (compound 22a), an eqBuChE (equine serum-derived butyrylcholinesterase) inhibitor, exhibits potent activity with an IC50 of 173 nM. In addition to eqBuChE, it also inhibits human BACE1, Aβ aggregation, and mouse GABA transporters 1 and 4 (mGAT1 and mGAT4) . Notably, BuChE-IN-9 demonstrates significant antiamnesic properties [1].

Molecular Formula

C28H34N4O2

Molecular Weight

458.6

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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