FLT3-IN-22
Product Specifications
Target
Others|||FLT
Related Pathways
Tyrosine Kinase/Adaptors|||Others|||Angiogenesis
Bioactivity
FLT3-IN-22 (compound 22f) is a potent FLT3 inhibitor with IC50 values of 0.941 nM for FLT3 and 0.199 nM for the FLT3/D835Y mutant. It demonstrates significant antiproliferative effects against MV4-11 cells and Ba/F3 cell lines expressing mutant FLT kinase variants, including FLT-D835Y and FLT3-F691L [1].
Molecular Formula
C24H22N6O2
Molecular Weight
426.47
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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