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FLT3-IN-22

Product Specifications

Target

Others|||FLT

Related Pathways

Tyrosine Kinase/Adaptors|||Others|||Angiogenesis

Bioactivity

FLT3-IN-22 (compound 22f) is a potent FLT3 inhibitor with IC50 values of 0.941 nM for FLT3 and 0.199 nM for the FLT3/D835Y mutant. It demonstrates significant antiproliferative effects against MV4-11 cells and Ba/F3 cell lines expressing mutant FLT kinase variants, including FLT-D835Y and FLT3-F691L [1].

Molecular Formula

C24H22N6O2

Molecular Weight

426.47

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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