BLT2 antagonist-1
Product Specifications
CAS Number
2069220-61-5
Target
Leukotriene Receptor
Related Pathways
GPCR/G Protein
Bioactivity
BLT2 antagonist-1 (compound 15b) is a selective inhibitor of the BLT2 receptor, impeding the chemotaxis of CHO-BLT2 cells at an IC50 of 224 nM without affecting CHO-BLT1 cell chemotaxis. It blocks the interaction between LTB4 and the BLT2 receptor with a K_i of 132 nM and may serve as a research tool for inflammatory airway diseases, including asthma and chronic obstructive pulmonary disease [1].
Smiles
N(CC1=CC=C(C=C1)C2=CC=C(OCC(O)=O)C=C2)(C(CCCC)=O)C3=CC(F)=CC=C3
Molecular Formula
C26H26FNO4
Molecular Weight
435.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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