PARP1-IN-15
Product Specifications
Target
Apoptosis, PARP
Related Pathways
Apoptosis, DNA Damage/DNA Repair, Chromatin/Epigenetic
Bioactivity
PARP1-IN-15 (Compound 6) is a PARP1 inhibitor that also inhibits tankyrase (TNKS) and promotes DNA double-strand breaks, leading to tumor cell apoptosis. It exhibits anti-cancer activity in triple-negative breast cancer (TNBC) cells and patient-derived organoids, making it useful for TNBC research, including cases with or without BRCA1 mutations [1].
Molecular Formula
C16H12N2O2
Molecular Weight
264.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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