A09-003
Product Specifications
CAS Number
2911646-14-3
Target
Bcl-2 Family|||Apoptosis|||CDK
Related Pathways
Cell Cycle/Checkpoint|||Apoptosis
Purity
0.9984
Bioactivity
A09-003 is a novel cell cycle protein-dependent kinase-9 CDK-9 inhibitor.A09-003 inhibits the proliferation of a variety of leukemia cell lines and inhibits the increase of leukemia sequence-1 protein in myeloid cells.A09-003 also induces apoptosis, decreases RNA polymerase II activity, and decreases Mcl-1 expression.
Smiles
N=1C=CC(=CC1NC2=CC=CC(=C2)N3CCNCCC3)C=4C=CC=CC4OC
Molecular Formula
C23H26N4O
Molecular Weight
374.48
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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