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VEGFR-2-IN-36

Product Specifications

Target

Apoptosis, Bcl-2 Family, VEGFR

Related Pathways

Apoptosis, Angiogenesis, Tyrosine Kinase/Adaptors

Bioactivity

VEGFR-2-IN-36 (compound 15) is a potent VEGFR-2 inhibitor with an IC50 value of 0.067 μM and acts as an apoptosis inducer with demonstrated anticancer efficacy, modulating apoptotic pathways by upregulating BAX and downregulating Bcl-2, leading to cytotoxic effects on cancer cell lines, including MCF-7 (IC50 = 0.42 μM) and HepG2 (IC50 = 0.22 μM) [1].

Molecular Formula

C24H23N7O5

Molecular Weight

489.48

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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