VEGFR-2-IN-36
Product Specifications
Target
Apoptosis, Bcl-2 Family, VEGFR
Related Pathways
Apoptosis, Angiogenesis, Tyrosine Kinase/Adaptors
Bioactivity
VEGFR-2-IN-36 (compound 15) is a potent VEGFR-2 inhibitor with an IC50 value of 0.067 μM and acts as an apoptosis inducer with demonstrated anticancer efficacy, modulating apoptotic pathways by upregulating BAX and downregulating Bcl-2, leading to cytotoxic effects on cancer cell lines, including MCF-7 (IC50 = 0.42 μM) and HepG2 (IC50 = 0.22 μM) [1].
Molecular Formula
C24H23N7O5
Molecular Weight
489.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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