ZMF-23
Product Specifications
Target
PAK|||HDAC
Related Pathways
Chromatin/Epigenetic|||DNA Damage/DNA Repair|||Cytoskeletal Signaling
Bioactivity
ZMF-23, a PAK1/HDAC6 dual inhibitor, suppresses PAK1 and HDAC6-mediated aerobic glycolysis and cellular migration while inducing TNF-?-regulated necroptosis and augmenting apoptosis. The compound effectively hampers the Warburg effect and cell motility, positioning it as a potential research tool for triple-negative breast cancer (TNBC) [1].
Molecular Formula
C22H23Cl2N5O3
Molecular Weight
476.36
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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