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COX-2/15-LOX-IN-3

Product Specifications

Target

Lipoxygenase, COX

Related Pathways

Neuroscience, Metabolism, Immunology/Inflammation

Bioactivity

COX-2/15-LOX-IN-3 (compound 5k) is a dual inhibitor of COX-2 and 15-LOX with inhibitory concentrations (IC50) of 0.075 μM and 1.97 μM, respectively. This compound effectively suppresses LPS-induced production of pro-inflammatory cytokines (IL-6, ROS, and NO), exhibiting targeted anti-inflammatory effects [1].

Molecular Formula

C25H24FN3O3S

Molecular Weight

465.54

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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