COX-2/15-LOX-IN-3
Product Specifications
Target
Lipoxygenase, COX
Related Pathways
Neuroscience, Metabolism, Immunology/Inflammation
Bioactivity
COX-2/15-LOX-IN-3 (compound 5k) is a dual inhibitor of COX-2 and 15-LOX with inhibitory concentrations (IC50) of 0.075 μM and 1.97 μM, respectively. This compound effectively suppresses LPS-induced production of pro-inflammatory cytokines (IL-6, ROS, and NO), exhibiting targeted anti-inflammatory effects [1].
Molecular Formula
C25H24FN3O3S
Molecular Weight
465.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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