Anticancer agent 147
Product Specifications
CAS Number
2241283-11-2
Target
Ferroptosis
Related Pathways
Apoptosis
Bioactivity
Compound 6j (Anticancer agent 147), a sophoridine derivative and ferroptosis inducer, promotes intracellular accumulation of Fe2+, reactive oxygen species (ROS), and malondialdehyde (MDA), enhances endoplasmic reticulum (ER) stress, and upregulates activating transcription factor 3 (ATF3) expression, demonstrating potent anti-liver cancer effects both in vitro and in vivo [1].
Smiles
C(CCC(OC)=O)[C@@H]1[C@@]2([C@@]3([C@@](CN1CC=4C=5C(N(CC6=CC=C(Br)C=C6)C4)=CC=CC5)(CCCN3CCC2)[H])[H])[H]
Molecular Formula
C32H40BrN3O2
Molecular Weight
578.58
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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