IRAK4-IN-28
Product Specifications
CAS Number
2952532-92-0
Target
IRAK
Related Pathways
NF-κB, Immunology/Inflammation
Bioactivity
IRAK4-IN-28 (compound 42), an orally-active IRAK4 inhibitor (IC50=8.9 nM), exhibits strong binding affinity with a Kd of 0.58 nM for the target enzyme. It is utilized for research purposes in the study of inflammation and autoimmune diseases [1].
Smiles
C(NC=1N=C(C=CC1)C=2C=NN(C)C2)(=O)C3=C(N=C4C(=C3)OC(=N4)N5CCOCC5)N6CCN(CC6)C7CC7
Molecular Formula
C27H31N9O3
Molecular Weight
529.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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